Regional cerebral blood flow after controlled cortical impact injury in rats.

@article{Bryan1995RegionalCB,
  title={Regional cerebral blood flow after controlled cortical impact injury in rats.},
  author={Robert M. Jr. Bryan and Leela Cherian and Claudia Sue Robertson},
  journal={Anesthesia and analgesia},
  year={1995},
  volume={80 4},
  pages={687-95}
}
Regional cerebral blood flow (rCBF) and laser-Doppler perfusion were measured in rats after controlled cortical impact injury (CCII), a model of traumatic brain injury. Male Long-Evans rats were anesthetized with isoflurane and surgically prepared with arterial and venous cannulae. CCII was induced after a craniectomy by deforming the right parietal cortex to a depth of 2 mm with a metal cylinder traveling at a velocity of 5.2 m/s. Laser-Doppler perfusion was monitored from the surface of the… CONTINUE READING