Regional brain atrophy and functional disconnection across Alzheimer's disease evolution.

Abstract

OBJECTIVE To assess the contribution of regional grey matter (GM) atrophy and functional disconnection in determining the level of cognitive decline in patients with Alzheimer's disease (AD) at different clinical stages. METHODS Ten patients with amnesic mild cognitive impairment (a-MCI), 11 patients with probable AD and 10 healthy controls were recruited… (More)
DOI: 10.1136/jnnp.2009.199935

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