Regional assignment of human tissue factor gene (F3) to chromosome 1p21-p22

@article{Kao1988RegionalAO,
  title={Regional assignment of human tissue factor gene (F3) to chromosome 1p21-p22},
  author={F. T. Kao and J Hartz and Renata Horton and Yale Nemerson and S. D. Carson},
  journal={Somatic Cell and Molecular Genetics},
  year={1988},
  volume={14},
  pages={407-410}
}
Tissue factor, or coagulation factor III, is a membrane-bound glycoprotein and acts as a cofactor for factor VII-dependent initiation of blood coagulation. The tissue factor gene (F3) was previously assigned to human chromosome 1, region p21-pter. The present report has further refined the mapping position to 1p21-p22 using a cDNA probe for the tissue factor gene and in situ hybridization to metaphase chromosomes.