Regional and time-resolved mutation patterns of the human genome

@article{Arndt2003RegionalAT,
  title={Regional and time-resolved mutation patterns of the human genome},
  author={Peter F. Arndt and Terence Hwa},
  journal={Bioinformatics},
  year={2003},
  volume={20 10},
  pages={1482-5}
}
MOTIVATION Substantial regional variations of substitutional processes have recently been reported from human/mouse comparisons. However, several features including the C + G dependence and the CpG-based transition effect remain obscure. RESULTS Utilizing the vast amount of transposable elements in the human genome, we performed detailed analysis of the substitutional and insertion/deletion patterns along the human lineage in a regional and time-resolved fashion. We observed a drastic… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…