Regional and temporal differences in real-time dopamine efflux in the nucleus accumbens during free-choice novelty.

@article{Rebec1997RegionalAT,
  title={Regional and temporal differences in real-time dopamine efflux in the nucleus accumbens during free-choice novelty.},
  author={George V Rebec and Jeppe Romme Christensen and Camino Guerra and Michael T. Bardo},
  journal={Brain research},
  year={1997},
  volume={776 1-2},
  pages={61-7}
}
To assess dopamine efflux during novelty-seeking behavior in rats, fast-scan cyclic voltammetry in the nucleus accumbens was combined with free-choice entry into a novel environment. Cyclic voltammograms, confirmed by in vitro testing, revealed that entry into novel, but not familiar, surroundings increased dopamine efflux in a regionally and temporally… CONTINUE READING