Regional- and temporal-dependent changes in the differentiation of Olig2 progenitors in the forebrain, and the impact on astrocyte development in the dorsal pallium.

@article{Ono2008RegionalAT,
  title={Regional- and temporal-dependent changes in the differentiation of Olig2 progenitors in the forebrain, and the impact on astrocyte development in the dorsal pallium.},
  author={Katsuhiko Ono and Hirohide Takebayashi and Kazuyo Ikeda and Miki Furusho and Takumi Nishizawa and Keisuke Watanabe and Kazuhiro Ikenaka},
  journal={Developmental biology},
  year={2008},
  volume={320 2},
  pages={456-68}
}
Olig2 is a basic helix-loop-helix transcription factor essential for oligodendrocyte and motoneuron development in the spinal cord. Olig2-positive (Olig2+) cells in the ventricular zone of the ventral telencephalon have been shown to differentiate into GABAergic and cholinergic neurons. However, the fate of Olig2 lineage cells in the postnatal forebrain has not been fully described and Olig2 may regulate the development of both astrocytes and oligodendrocytes. Here, we examined the fate of… CONTINUE READING

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