Regional and cellular expression of glial (GLT1) and neuronal (EAAC1) glutamate transporter proteins in ovine fetal brain

@article{Northington1998RegionalAC,
  title={Regional and cellular expression of glial (GLT1) and neuronal (EAAC1) glutamate transporter proteins in ovine fetal brain},
  author={Frances J. Northington and Richard J. Traystman and Raymond C. Koehler and Jeffrey D Rothstein and Lee J. Martin},
  journal={Neuroscience},
  year={1998},
  volume={85},
  pages={1183-1193}
}
Glutamate transport is a primary mechanism for regulating extracellular levels of glutamate which can have either neurotrophic or neurotoxic effects in the developing brain, depending on its concentration. Using immunoblotting and immunocytochemistry, we tested the hypotheses that expression of neuronal and glial glutamate transporter proteins was regionally and temporally regulated in the developing ovine brain and that expression of the glial isoform early in development was not cell-type… CONTINUE READING
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