Regional Slow Waves and Spindles in Human Sleep

  title={Regional Slow Waves and Spindles in Human Sleep},
  author={Yuval Nir and Richard Staba and Thomas Andrillon and Vladyslav V Vyazovskiy and Chiara Cirelli and Itzhak Fried and Giulio Tononi},
The most prominent EEG events in sleep are slow waves, reflecting a slow (<1 Hz) oscillation between up and down states in cortical neurons. It is unknown whether slow oscillations are synchronous across the majority or the minority of brain regions--are they a global or local phenomenon? To examine this, we recorded simultaneously scalp EEG, intracerebral EEG, and unit firing in multiple brain regions of neurosurgical patients. We find that most sleep slow waves and the underlying active and… CONTINUE READING
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