Regional MeCP2 expression levels in the female MeCP2-deficient mouse brain correlate with specific behavioral impairments.

Abstract

Using female MeCP2-deficient mice as a model, we tested whether MeCP2 expression levels would parallel one another in different regions of the brain and spinal cord, and/or whether the levels of MeCP2 protein in these specific neural regions would correlate with the degree of behavioral impairment seen in individual subjects. Our results show that MeCP2… (More)
DOI: 10.1016/j.expneurol.2012.09.005

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