Regional Differences in the Ontogeny of the Serotonergic Projection to the Cerebral Cortex

@article{Dori1996RegionalDI,
  title={Regional Differences in the Ontogeny of the Serotonergic Projection to the Cerebral Cortex},
  author={Ioanna Dori and Athanasios Dinopoulos and Mary E Blue and John G. Parnavelas},
  journal={Experimental Neurology},
  year={1996},
  volume={138},
  pages={1-14}
}
We used light and electron microscope immunocytochemistry to compare the development of the pattern of innervation and synaptic organization of the serotonin (5-HT) afferent system in sensory (visual and somatosensory) and motor areas of the rat cerebral cortex. Serotonin-labeled fibers were present in all cortical areas at birth appearing as two tangential streams, one above and one below the cortical plate. These fibers gradually arborized sending branches into all cortical layers in an… CONTINUE READING

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