Regional Brain Atrophy and Functional Disconnection in Broca’s Area in Individuals at Ultra-High Risk for Psychosis and Schizophrenia

@inproceedings{Jung2012RegionalBA,
  title={Regional Brain Atrophy and Functional Disconnection in Broca’s Area in Individuals at Ultra-High Risk for Psychosis and Schizophrenia},
  author={Wi Hoon Jung and Joon Hwan Jang and Na young Shin and Sung Nyun Kim and Chi-Hoon Choi and Suk K. An and Jun Soo Kwon},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND Abnormalities in cognitive abilities such as verbal fluency and in cognitive-related brain regions, particularly Broca's area, have been reported in patients with schizophrenia. Additionally, previous studies have demonstrated that structural and functional abnormalities in Broca's area were associated with clinical symptoms and cognitive deficits in patients with schizophrenia, suggesting that deficits in this area may reflect the core pathology of schizophrenia. Thus, it is… CONTINUE READING