Region-specific neural induction of an engrailed protein by anterior notochord in Xenopus.

@article{HemmatiBrivanlou1990RegionspecificNI,
  title={Region-specific neural induction of an engrailed protein by anterior notochord in Xenopus.},
  author={Ali Hemmati-Brivanlou and R. Malcolm Stewart and Richard M Harland},
  journal={Science},
  year={1990},
  volume={250 4982},
  pages={800-2}
}
Anterior-specific neural induction can be assayed by means of an antibody that recognizes the Xenopus homeobox-containing protein En-2. The En-2 antigen is an excellent early marker, since it is present as a discrete band in the anterior neural plate of neurula embryos. Regional induction was assayed by combining dorsal mesoderm with competent ectoderm. Anterior notochord from the early neurula induced En-2 frequently, while posterior notochord induced En-2 less frequently. Presumptive somitic… CONTINUE READING

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