Region-specific insertion of transposons in combination with selection for high plasmid transferability and stability accounts for the structural similarity of IncP-1 plasmids.

@article{Sota2007RegionspecificIO,
  title={Region-specific insertion of transposons in combination with selection for high plasmid transferability and stability accounts for the structural similarity of IncP-1 plasmids.},
  author={Masahiro Sota and Masataka Tsuda and Hirokazu Yano and Haruo Suzuki and Larry J. Forney and Eva M Top},
  journal={Journal of bacteriology},
  year={2007},
  volume={189 8},
  pages={3091-8}
}
The overall architecture of IncP-1 plasmids is very conserved in that the accessory genes are typically located in one or two specific regions: between oriV and trfA and between the tra and trb operons. Various hypotheses have been formulated to explain this, but none have been tested experimentally. We investigated whether this structural similarity is due to region-specific transposition alone or also is reliant on selection for plasmids with insertions limited to these two regions. We first… CONTINUE READING

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Stability of a promiscuous plasmid in different hosts: no guarantee for a long-term relationship

  • L. De Gelder, J. M. Ponciano, P. Joyce, E. M. Top
  • Microbiology
  • 2007
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