Region specific distribution of levomepromazine in the human brain

@article{Kornhuber2005RegionSD,
  title={Region specific distribution of levomepromazine in the human brain},
  author={J. Kornhuber and H. Weigmann and J. R{\"o}hrich and J. Wiltfang and S. Bleich and I. Meineke and R. Z{\"o}chling and S. H{\"a}rtter and P. Riederer and C. Hiemke},
  journal={Journal of Neural Transmission},
  year={2005},
  volume={113},
  pages={387-397}
}
Summary.Objective: The aim of this study was to examine concentrations of levomepromazine and its metabolite desmethyl-levomepromazine in different regions of human brain and in relationship to drug-free time.Methods: Drug concentrations were measured in up to 43 regions of 5 postmortem human brains of patients previously treated with levomepromazine. To enable statistical comparison across brain regions several smaller brain areas were put together to form larger brain areas (cortex cerebri… Expand
Neuroleptic drugs in the human brain
Cerebral microdialysis in clinical studies of drugs: pharmacokinetic applications
Actions of psychotropic drugs beyond their primary targets at the synaptic cleft
Effects of diverse psychopharmacological substances on the activity of brain prolyl oligopeptidase.
Bioanalytical methods for the determination of antipsychotic drugs.
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