Region-specific differentiation of embryonic stem cell-derived neural progenitor transplants into the adult mouse hippocampus following seizures.

@article{Carpentino2008RegionspecificDO,
  title={Region-specific differentiation of embryonic stem cell-derived neural progenitor transplants into the adult mouse hippocampus following seizures.},
  author={Joseph E. Carpentino and Nathaniel W. Hartman and Laura B. Grabel and Janice R Naegele},
  journal={Journal of neuroscience research},
  year={2008},
  volume={86 3},
  pages={512-24}
}
Embryonic stem (ES) cells can generate neural progenitors and neurons in vitro and incorporate into the adult central nervous system (CNS) following transplantation, suggesting their therapeutic potential for treating neurological disorders. However, our understanding of the conditions that direct ES-derived neural progenitor (ESNP) migration and… CONTINUE READING