Region and tissue differences of metabolites in normally aged brain using multislice 1H magnetic resonance spectroscopic imaging.

@article{Schuff2001RegionAT,
  title={Region and tissue differences of metabolites in normally aged brain using multislice 1H magnetic resonance spectroscopic imaging.},
  author={Norbert Schuff and Frank Ezekiel and Anthony Collins Gamst and Diane L Amend and Andres A Capizzano and Andrew A. Maudsley and Michael W Weiner},
  journal={Magnetic resonance in medicine},
  year={2001},
  volume={45 5},
  pages={899-907}
}
Quantitative measurements of regional and tissue specific concentrations of brain metabolites were measured in elderly subjects using multislice proton magnetic resonance spectroscopic imaging ((1)H MRSI). Selective k-space extrapolation and an inversion-recovery sequence were used to minimize lipid contamination and linear regression was used to account for partial volume problems. The technique was applied to measure the concentrations of N-acetyl aspartate (NAA), and creatine (Cr)- and… CONTINUE READING

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