Regioisomeric differentiation of mono-methoxy ring-substituted amphetamine and methamphetamine by GC-MS

@inproceedings{Liu2003RegioisomericDO,
  title={Regioisomeric differentiation of mono-methoxy ring-substituted amphetamine and methamphetamine by GC-MS},
  author={Ju-tsung Liu and Main-ping Sun and Yun-shun Tsai},
  year={2003}
}
The 2-, 3-, and 4-methoxyamphetamines and methoxymethamphetamines were prepared and analyzed by GC-MS. Regioisomerism at the aromatic ring in these compounds possess similar analytical properties. They show similar gas chromatographic retention properties on a column with phenylmethylsilicone (HP-5) stationary phase. The mass spectra for the underivatized amines are similar and fail to provide sufficient information to differentiate the ring regioisomers. Preparation of the… CONTINUE READING

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