Regenerative medicine and human models of human disease

@article{Chien2008RegenerativeMA,
  title={Regenerative medicine and human models of human disease},
  author={Kenneth R. Chien},
  journal={Nature},
  year={2008},
  volume={453},
  pages={302-305}
}
Recent advances in stem-cell technology are now allowing the mechanisms of human disease to be studied in human cells. A new era for regenerative medicine is arising from such disease models, extending beyond early cell-based therapies and towards evaluating genetic variation in humans and identifying the molecular pathways that lead to disease, as well as targets for therapy.