Regenerative capacity of human satellite cells: the mitotic clock in cell transplantation

@article{Donna2000RegenerativeCO,
  title={Regenerative capacity of human satellite cells: the mitotic clock in cell transplantation},
  author={S Di Donna and Val{\'e}rie Renault and Christian Forestier and G. Piron-Hamelin and D. Thiesson and Racquel N. Cooper and Ernesto Ponsot and St{\'e}phanie Decary and Rim Amouri and Fayçel Hentati and Gillian Sandra Butler-Browne and V. Mouly},
  journal={Neurological Sciences},
  year={2000},
  volume={21},
  pages={S943-S951}
}
Abstract In this communication, we will review the problems caused by cell-mediated gene therapy, taking skeletal muscle as a physiological model. In particular we have utilised vectors transferring telomerase under the control of retroviral promoters into human satellite cells. The set of results presented here has several implications regarding gene therapy trials. Nevertheless, more experiments will be required to fully validate this cellular model and to use telomerase to safely extend the… CONTINUE READING

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