Regenerative and fibrotic pathways in canine hepatic portosystemic shunt and portal vein hypoplasia, new models for clinical hepatocyte growth factor treatment

Abstract

BACKGROUND We analyzed two spontaneous dog diseases characterized by subnormal portal perfusion and reduced liver growth: (i) congenital portosystemic shunts (CPSS) without fibrosis and (ii) primary portal vein hypoplasia (PPVH), a disease associated with fibrosis. These pathologies, that lack inflammation or cholestasis, may represent simplified models to… (More)

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Cite this paper

@article{Spee2005RegenerativeAF, title={Regenerative and fibrotic pathways in canine hepatic portosystemic shunt and portal vein hypoplasia, new models for clinical hepatocyte growth factor treatment}, author={Bart Spee and Louis C. Penning and Ted S. G. A. M. van den Ingh and Brigitte Arends and Jooske Ijzer and Frederik J van Sluijs and Jan Rothuizen}, journal={Comparative Hepatology}, year={2005}, volume={4}, pages={7 - 7} }