Regenerative Therapies for Diabetic Microangiopathy

  title={Regenerative Therapies for Diabetic Microangiopathy},
  author={Roberto Bassi and Alessio Trevisani and Sara Tezza and Moufida Ben Nasr and Francesca Gatti and Andrea Vergani and Antonio Farina and Paolo Fiorina},
  booktitle={Experimental diabetes research},
Hyperglycaemia occurring in diabetes is responsible for accelerated arterial remodeling and atherosclerosis, affecting the macro- and the microcirculatory system. Vessel injury is mainly related to deregulation of glucose homeostasis and insulin/insulin-precursors production, generation of advanced glycation end-products, reduction in nitric oxide synthesis, and oxidative and reductive stress. It occurs both at extracellular level with increased calcium and matrix proteins deposition and at… CONTINUE READING
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