Regeneration versus scarring in vertebrate appendages and heart

@inproceedings{Jawiska2016RegenerationVS,
  title={Regeneration versus scarring in vertebrate appendages and heart},
  author={Anna Jaźwińska and Pauline Sallin},
  booktitle={The Journal of pathology},
  year={2016}
}
Injuries to complex human organs, such as the limbs and the heart, result in pathological conditions, for which we often lack adequate treatments. While modern regenerative approaches are based on the transplantation of stem cell-derived cells, natural regeneration in lower vertebrates, such as zebrafish and newts, relies predominantly on the intrinsic plasticity of mature tissues. This property involves local activation of the remaining material at the site of injury to promote cell division… CONTINUE READING
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Evolution, comparative biology and ontogeny of vertebrate heart regeneration

  • npj Regenerative Medicine
  • 2016
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