Regeneration of the motor component of the rat sciatic nerve with local administration of neurotrophic growth factor in silicone chambers.


The experimental model reported consists of a subcutaneous reservoir connected to a rat sciatic nerve anastomosis. The right sciatic nerve was exposed, served, and repaired at a level 1.5 cm proximal to its trifurcation. Then, a dome-shaped silicone reservoir, connected to the proximal end of a silicone tube, was placed subcutaneously in the dorsum of the… (More)


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