Regeneration of neural crest derivatives in the Xenopus tadpole tail

  title={Regeneration of neural crest derivatives in the Xenopus tadpole tail},
  author={Gufa Lin and Ying Chen and Jonathan Mw Slack},
  journal={BMC Developmental Biology},
  pages={56 - 56}
After amputation of the Xenopus tadpole tail, a functionally competent new tail is regenerated. It contains spinal cord, notochord and muscle, each of which has previously been shown to derive from the corresponding tissue in the stump. The regeneration of the neural crest derivatives has not previously been examined and is described in this paper. Labelling of the spinal cord by electroporation, or by orthotopic grafting of transgenic tissue expressing GFP, shows that no cells emigrate from… CONTINUE READING
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Xenopus tadpole tail regeneration requires the activity of the proton pump V-ATPase, and proton pumping is sufficient to partially rescue the loss of function phenotype

  • DS Adams, A Masi, M Levin
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  • 2006
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