Regeneration of mammalian skeletal muscle. Basic mechanisms and clinical implications.

@article{Ciciliot2010RegenerationOM,
  title={Regeneration of mammalian skeletal muscle. Basic mechanisms and clinical implications.},
  author={Stefano Ciciliot and Stefano Schiaffino},
  journal={Current pharmaceutical design},
  year={2010},
  volume={16 8},
  pages={
          906-14
        }
}
Mammalian skeletal muscles can regenerate following injury and this response is mediated by a specific type of stem cell, the satellite cell. We review here the three main phases of muscle regeneration, including i) the initial inflammatory response and the dual role of macrophages as both scavengers involved in the phagocytosis of necrotic debris and… CONTINUE READING