Regeneration of human infarcted heart muscle by intracoronary autologous bone marrow cell transplantation in chronic coronary artery disease: the IACT Study.

@article{Strauer2005RegenerationOH,
  title={Regeneration of human infarcted heart muscle by intracoronary autologous bone marrow cell transplantation in chronic coronary artery disease: the IACT Study.},
  author={Bodo Eckehard Strauer and Michael Brehm and Tobias Zeus and Thomas Bartsch and Christina Mira Schannwell and Christine Antke and R{\"u}diger Volker Sorg and Gesine Koegler and Peter Wernet and H M{\"u}ller and Matthias K{\"o}stering},
  journal={Journal of the American College of Cardiology},
  year={2005},
  volume={46 9},
  pages={1651-8}
}
OBJECTIVES Stem cell therapy may be useful in chronic myocardial infarction (MI); this is conceivable, but not yet demonstrated in humans. BACKGROUND After acute MI, bone marrow-derived cells improve cardiac function. METHODS We treated 18 consecutive patients with chronic MI (5 months to 8.5 years old) by the intracoronary transplantation of autologous bone marrow mononuclear cells and compared them with a representative control group without cell therapy. RESULTS After three months, in… CONTINUE READING
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