Regeneration of full-thickness skin defects using umbilical cord blood stem cells loaded into modified porous scaffolds.

@article{Zeinali2014RegenerationOF,
  title={Regeneration of full-thickness skin defects using umbilical cord blood stem cells loaded into modified porous scaffolds.},
  author={Reza Zeinali and Esmaeil Biazar and Saeed Heidari Keshel and Mostafa Rezaei Tavirani and Kamal Asadipour},
  journal={ASAIO journal},
  year={2014},
  volume={60 1},
  pages={106-14}
}
In this study, we have demonstrated the ability of cord blood (CB)-derived unrestricted somatic stem cells (USSCs) and chitosan-modified poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) scaffold to promote skin regeneration. Afterward, the scaffolds were evaluated by structural, microscopic, physical, and mechanical assays and cell culture analyses. Results of structural, physical, and mechanical analyses also showed a good resilience and compliance with movement as a skin graft. Cellular… CONTINUE READING
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