Regeneration of a central synapse restores nonassociative learning.

@article{Modney1997RegenerationOA,
  title={Regeneration of a central synapse restores nonassociative learning.},
  author={B K Modney and Christie L. Sahley and Kenneth J. Muller},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1997},
  volume={17 16},
  pages={6478-82}
}
Sensitization is a form of nonassociative learning in which a strong or noxious stimulus persistently enhances the response produced by a weaker stimulus. In the leech Hirudo medicinalis, the S-interneuron is required for sensitization of the shortening response. A single S-cell axon was surgically separated from its sole synaptic partner, the neighboring S-cell. This consistently eliminated sensitization without impairing reflexive shortening itself, as measured in semi-intact specimens… CONTINUE READING

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