Regeneration of Pancreatic Islets in Vivo by Ultrasound-Targeted Gene Therapy

Abstract

This study uses a novel approach to gene therapy in which plasmid DNA is targeted to the pancreas in vivo using ultrasound-targeted microbubble destruction (UTMD) to achieve islet regeneration. Intravenous microbubbles carrying plasmids are destroyed within the pancreatic microcirculation by ultrasound, achieving local gene expression that is further… (More)
DOI: 10.1038/gt.2010.85

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Cite this paper

@inproceedings{Chen2010RegenerationOP, title={Regeneration of Pancreatic Islets in Vivo by Ultrasound-Targeted Gene Therapy}, author={Shuyuan Chen and M. Shimoda and May-yun Wang and Jiahuan Ding and Hirofumi Noguchi and Shinichi Matsumoto and Paul Artur Grayburn}, booktitle={Gene Therapy}, year={2010} }