Regeneration following tibial nerve crush in the rabbit: the effect of proximal constriction.

@article{Reiners1987RegenerationFT,
  title={Regeneration following tibial nerve crush in the rabbit: the effect of proximal constriction.},
  author={Karlheinz Reiners and R. W. Gilliatt and Anita E. Harding and J. H. O'Neill},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={1987},
  volume={50 1},
  pages={6-11}
}
In order to test the regenerative capacity of atrophic axons, a constricting ligature was placed around the proximal tibial nerve of the rabbit, and the nerve crushed at the ankle one week later. Axonal atrophy with altered g ratios was subsequently confirmed in fibres distal to the site of ligature and proximal to the site of crush. In nerves with tight proximal ligatures the reinnervation of plantar muscles and the subsequent recovery of distal motor latency were delayed, indicating impaired… CONTINUE READING

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