Regenerating optic pathways from the eye to the brain

@article{Laha2017RegeneratingOP,
  title={Regenerating optic pathways from the eye to the brain},
  author={Bireswar Laha and Ben K. Stafford and Andrew D Huberman},
  journal={Science},
  year={2017},
  volume={356},
  pages={1031-1034}
}
Humans are highly visual. Retinal ganglion cells (RGCs), the neurons that connect the eyes to the brain, fail to regenerate after damage, eventually leading to blindness. Here, we review research on regeneration and repair of the optic system. Intrinsic developmental growth programs can be reactivated in RGCs, neural activity can enhance RGC regeneration, and functional reformation of eye-to-brain connections is possible, even in the adult brain. Transplantation and gene therapy may serve to… CONTINUE READING

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Glaucoma Research Foundation, the McKnight Foundation, the Pew Charitable Trusts, and the E. Matilda Ziegler Foundation for the Blind. 10.1126/science.aal5060 Laha et al., Science

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