Regenerating functional heart tissue for myocardial repair

  title={Regenerating functional heart tissue for myocardial repair},
  author={Andre W Alcon and Esra Cagavi Bozkulak and Yibing Qyang},
  journal={Cellular and Molecular Life Sciences},
Heart disease is one of the leading causes of death worldwide and the number of patients with the disease is likely to grow with the continual decline in health for most of the developed world. Heart transplantation is one of the only treatment options for heart failure due to an acute myocardial infarction, but limited donor supply and organ rejection limit its widespread use. Cellular cardiomyoplasty, or cellular implantation, combined with various tissue-engineering methods aims to… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Explore Further: Topics Discussed in This Paper


Publications citing this paper.
Showing 1-10 of 16 extracted citations

Development of a three-dimensional pre-vascularized scaffold-free contractile cardiac patch for treating heart disease.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation • 2016
View 1 Excerpt

The heart of the matter : cardiac stem cells

Esra Cagavi, Arzuhan Koc, Sevilay ŞAHOĞLU GÖKTAŞ
View 2 Excerpts


Publications referenced by this paper.
Showing 1-10 of 182 references

Nongenetic method for purifying stem cell–derived cardiomyocytes

Nature Methods • 2010
View 6 Excerpts
Highly Influenced

Prevascularization of cardiac patch on the omentum improves its therapeutic outcome.

Proceedings of the National Academy of Sciences of the United States of America • 2009
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…