Reg (regenerating) gene overexpression in islets from non-obese diabetic mice with accelerated diabetes: role of IFNβ

Abstract

The expression of IFNβ in beta cells results in accelerated type 1 diabetes. The REG family of beta cell proliferation factors have been described as autoantigens in autoimmune diabetes. The aim of this study was to determine the effect of IFNβ on Reg expression, and the implications of this in terms of autoimmunity. Reg gene expression was determined in… (More)
DOI: 10.1007/s00125-006-0365-6

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@article{Planas2006RegG, title={Reg (regenerating) gene overexpression in islets from non-obese diabetic mice with accelerated diabetes: role of IFNβ}, author={Raquel Planas and Aurora Alba and Jorge Carrillo and Mar{\'i}a Del Carmen Puertas and R. Ampudia and Xavier Pastor and Hiroshi Okamoto and Shin Takasawa and Werner K Gurr and Ricardo Pujol-Borrell and Joan Verdaguer and Marta Vives-Pi}, journal={Diabetologia}, year={2006}, volume={49}, pages={2379-2387} }