Refractory sprue, coeliac disease, and enteropathy-associated T-cell lymphoma

@article{Cellier2000RefractorySC,
  title={Refractory sprue, coeliac disease, and enteropathy-associated T-cell lymphoma},
  author={Christophe Cellier and Eric Delabesse and Christine Helmer and Natacha Patey and for the French Coeliac Disease Study Group},
  journal={The Lancet},
  year={2000},
  volume={356},
  pages={203-208}
}
BACKGROUND Adult refractory sprue is a poorly defined disorder. We did a multicentre national study of patients with refractory sprue to characterise their clinical and pathological profile and outcome, and to assess the frequency and prognostic significance of phenotypic and molecular abnormalities in the intraepithelial T-cell population. METHODS Patients with severe symptomatic villous atrophy mimicking coeliac disease but refractory to a strict gluten-free diet, and with no initial… CONTINUE READING
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