Refractory periods and climate forcing in cholera dynamics

@article{Koelle2005RefractoryPA,
  title={Refractory periods and climate forcing in cholera dynamics},
  author={Katia Koelle and Xavier Rod{\'o} and Mercedes Pascual and Md. Yunus and Golam Mostafa},
  journal={Nature},
  year={2005},
  volume={436},
  pages={696-700}
}
Outbreaks of many infectious diseases, including cholera, malaria and dengue, vary over characteristic periods longer than 1 year. Evidence that climate variability drives these interannual cycles has been highly controversial, chiefly because it is difficult to isolate the contribution of environmental forcing while taking into account nonlinear epidemiological dynamics generated by mechanisms such as host immunity. Here we show that a critical interplay of environmental forcing, specifically… CONTINUE READING

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