Refractory period fluid stimulation of right atria: a method for studying presynaptic receptors in cardiac autonomic transmission.

A method is described for measuring the atrial period or beat interval from the surface electrogram in isolated spontaneously contracting guinea pig right atria. Stimulation of parasympathetic and sympathetic nerve endings can be readily obtained by applying electrical field pulses across the atria during the atrial refractory period to prevent arrhythmia… CONTINUE READING