Refractory iron deficiency anemia as the primary clinical manifestation of celiac disease.

@article{Mody2003RefractoryID,
  title={Refractory iron deficiency anemia as the primary clinical manifestation of celiac disease.},
  author={R. Mody and Pamela I. Brown and D. Wechsler},
  journal={Journal of pediatric hematology/oncology},
  year={2003},
  volume={25 2},
  pages={
          169-72
        }
}
In the absence of dietary insufficiency, iron deficiency is usually caused by chronic blood loss or intestinal malabsorption. Celiac disease is one of the most common causes of intestinal malabsorption during childhood, and its association with insulin-dependent diabetes mellitus has been previously reported. Here the authors describe an otherwise asymptomatic diabetic adolescent boy with iron deficiency anemia that was not responsive to oral iron therapy. A diagnosis of celiac disease was made… Expand
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Screening of celiac disease by anti-tissue transglutaminase antibody should be done as a routine investigation in children with iron-deficiency anemia, and biopsy should be recommended in patients withIron-deficient anemia who have positive celiac Disease serology. Expand
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The highest risk is for enteropathy associated T- cell lymphoma (EATL), an aggressive lymphoma with poor prognosis, however an increased risk for B-cell lymphomas and extraintestinal lymphomas has been described. Expand
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Celiac disease is not limited to the gastrointestinal tract and belongs to the group of autoimmune systemic diseases. It is frequently accompanied by a variety of extra digestive manifestations. More… Expand
Subclinical celiac disease in children: refractory iron deficiency as the sole presentation.
TLDR
The experience of a pediatric gastroenterology outpatient clinic attended by 63 CD patients, in 9 of whom refractory iron deficiency was the sole presentation at the time of diagnosis, shows that iron deficiency is quite common during childhood and often anticipated in certain ages such as infancy and adolescence. Expand
Hematologic manifestations of celiac disease.
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Patients with celiac disease are at increased risk of being diagnosed with lymphoma, especially of the T-cell type, and the risk is highest for enteropathy-type T- cell lymphoma (ETL) and B-cell lymphoma of the gut, but extraintestinal lymphomas can also be seen. Expand
Iron deficiency anemia.
  • S. F. Clark
  • Medicine
  • Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
  • 2008
TLDR
The prevalence of IDA related to confounding medical conditions will be described along with its diverse etiologies, and current diagnostic strategies that are inclusive of clinical presentation, biochemical tests, and differential diagnosis will be outlined, followed by a discussion of treatment modalities and future research recommendations. Expand
Refractory iron-deficiency anemia and gluten intolerance - Response to gluten-free diet.
TLDR
Age, anemia duration, number of transfusions,number of parenteral iron doses, and time on a gluten-free diet were compared according to the presence or absence of villous atrophy and HLA-DQ2/8 positivity, and no significant differences were found for any of the analyzed variables. Expand
Pathogenesis and clinical manifestation of celiac disease: analysis of atypical symptoms
Celiac disease is defined as enteropathy occurring after ingestion of gluten from cereals in genetically predisposed individuals. Recently, after introduction of sensitive and specific screening… Expand
Celiac disease in patients with an affected member, type 1 diabetes, iron-deficiency, or osteoporosis?
TLDR
In conclusion, significant reservoirs of CD can be found in some at-risk groups, such as those with T1DM, family members, and referred patients with osteoporosis and anemia, where it is not clear what impact CD has on the quality of life of these individuals. Expand
Anaemia , Iron Deficiency and Coeliac Disease
  • 2010
Anaemia and/or iron deficiency is a frequent laboratory finding in subjects with coeliac disease (CD). (1,2,3) Many studies have clearly shown that the clinical presentation of CD is very often… Expand
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