Refractory idiopathic urge urinary incontinence and botulinum A injection.

@article{Brubaker2008RefractoryIU,
  title={Refractory idiopathic urge urinary incontinence and botulinum A injection.},
  author={Linda Brubaker and Holly Elizabeth Richter and Anthony Visco and Sangeeta Tina Mahajan and Ingrid E. Nygaard and Thomas M Braun and Matthew D Barber and Shawn A. Menefee and Joseph Schaffer and Anne M. Weber and John Wei},
  journal={The Journal of urology},
  year={2008},
  volume={180 1},
  pages={217-22}
}
PURPOSE We compared 200 U intradetrusor botulinum toxin A vs placebo in women with refractory idiopathic urge incontinence. MATERIALS AND METHODS This institutional review board approved, multicenter registered trial randomized women with refractory urge incontinence, detrusor overactivity incontinence and 6 or greater urge incontinence episodes in 3 days to botulinum toxin A or placebo at a 2:1 ratio. Refractory was defined as inadequate symptom control after 2 or more attempts at… CONTINUE READING
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