• Chemistry
  • Published 1998

Refolding of recombinant proteins in vitro

  title={Refolding of recombinant proteins in vitro},
  author={Long Jy and Wang Hx},
Refolding of recombinant proteins is an important event in the downstream process of genetic engineering. On the basis of the mechanism of protein folding in vitro, general strategy of recombinant protein refolding is postulated, and major developments in recent years on this field are reviewed, including: molecular chaperone mediated refolding, detergentassisted refolding, protein refolding in reverse micelle, addition of folding enhancer and methods for the formation of disulfide bond… CONTINUE READING