Reflex increases in heart-rate induced by perfusing the hind leg of the rat with solutions containing lactic acid

Abstract

The hypothesis that metabolic receptors in skeletal muscle influence heart-rate during exercise was tested by means of a perfused preparation of the rat's hind legs. The isolated leg was connected to the body only by nerve and bone and was perfused with tyrode solution. The humoral changes of exercise were simulated by perfusing with modified tyrode… (More)
DOI: 10.1007/BF00581561

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