Reflectance speckle of retinal nerve fiber layer reveals axonal activity.

@article{Huang2013ReflectanceSO,
  title={Reflectance speckle of retinal nerve fiber layer reveals axonal activity.},
  author={Xiangrun Huang and Robert Knighton and Ye Zhou and Xiao-peng Zhao},
  journal={Investigative ophthalmology & visual science},
  year={2013},
  volume={54 4},
  pages={2616-23}
}
PURPOSE This study investigated the retinal nerve fiber layer (RNFL) reflectance speckle and tested the hypothesis that temporal change of RNFL speckle reveals axonal dynamic activity. METHODS RNFL reflectance speckle of isolated rat retinas was studied with monochromatic illumination. A series of reflectance images was collected every 5 seconds for approximately 15 minutes. Correlation coefficients (CC) of selected areas between a reference and subsequent images were calculated and plotted… CONTINUE READING

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