Refining genetic associations in multiple sclerosis

  title={Refining genetic associations in multiple sclerosis},
  author={Alexander I Tr{\"o}ster},
  booktitle={The Lancet Neurology},
Genome-wide association studies involve several hundred thousand markers and, even when quality control is scrupulous, are invariably confounded by residual uncorrected errors that can falsely infl ate the apparent diff erence between cases and controls (socalled genomic infl ation). As a consequence such studies inevitably generate false positives… CONTINUE READING