Refined localization of TSC1 by combined analysis of 9q34 and 16pl3 data in 14 tuberous sclerosis families

Abstract

Tuberous sclerosis (TSC) is a heterogeneous trait. Since 1990, linkage studies have yielded putative TSC loci on chromosomes 9, 11, 12 and 16. Our current analysis, performed on 14 Dutch and British families, reveals only evidence for loci on chromosome 9q34 (TSC1) and chromosome 16p13 (TSC2). We have found no indication for a third locus for TSC, linked or… (More)
DOI: 10.1007/BF00201608

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@article{Janssen1994RefinedLO, title={Refined localization of TSC1 by combined analysis of 9q34 and 16pl3 data in 14 tuberous sclerosis families}, author={Bart J Janssen and Julian R. Sampson and Mieke N. van der Est and Wout H. Deelen and Senno Verhoef and I R Daniels and Arjenne Hesseling and Phillip Thomas Brook-Carter and Mark D. Nellist and Dick Lindhout and Lodewijk A. Sandkuijl and Dicky J J Halley}, journal={Human Genetics}, year={1994}, volume={94}, pages={437-440} }