Refined chromosome analysis as an independent prognostic indicator in de novo myelodysplastic syndromes.

@article{Yunis1986RefinedCA,
  title={Refined chromosome analysis as an independent prognostic indicator in de novo myelodysplastic syndromes.},
  author={Juan Jos{\'e} Yunis and R. E. Rydell and Martin M. Oken and M A Arnesen and M G Mayer and Michael Lobell},
  journal={Blood},
  year={1986},
  volume={67 6},
  pages={1721-30}
}
In a study of 56 consecutive adult patients with de novo myelodysplastic syndromes (MDS), all cases were successfully analyzed with two refined chromosome banding techniques. Most patients (44 of 56, 79%) were found to have a chromosome defect. The majority of these patients had a recurrent loss of chromosomal material rather than a reciprocal translocation or inversion, as commonly found in acute leukemia. The three largest chromosomal categories found were associated with a wide range of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 42 extracted citations

New strategies in myelodysplastic syndromes: application of molecular diagnostics to clinical practice.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2013
View 1 Excerpt

Myelodysplastic syndromes.

American journal of clinical pathology • 2009

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Clinical implications of monosomy 7 in acute nonlymphocytic leukemia

GH Borgstrom, L Teerenhovi, +8 authors AA Sandberg
Br J Haematol • 1985

Herzin GP: High-dose cytosine arabinoside therapy with and without anthracydine antibiotics for remission reinduction of acute nonlymphoblastic leukemia

RA Herzig, HM Lazarus, WoIffSN, GL Phillips
i Clin Oncol • 1985

Similar Papers

Loading similar papers…