Referral patterns for microarray testing in prenatal diagnosis.

@article{Shaffer2012ReferralPF,
  title={Referral patterns for microarray testing in prenatal diagnosis.},
  author={Lisa Gail Shaffer and Mindy Preston Dabell and Jill A Rosenfeld and Nicholas J. Neill and Blake C. Ballif and Justine Coppinger and Noa Rinzler Diwan and Karen Chong and Mordechai Shohat and David C Chitayat},
  journal={Prenatal diagnosis},
  year={2012},
  volume={32 4},
  pages={
          344-50
        }
}
OBJECTIVE To understand the prenatal referral patterns from the United States, Canada, and Israel for two whole-genome microarray platforms, each with a different resolution. METHOD Physicians selected one of the two array designs to be performed on 1483 prenatal specimens for a 1-year period. We retrospectively examined detection rates, indications for study, and physician array selection. RESULTS The lower resolution array (55 K) showed an ~32% decrease in the detection of results of… CONTINUE READING
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