Reference values for methacholine reactivity (SAPALDIA study)

  title={Reference values for methacholine reactivity (SAPALDIA study)},
  author={Patrick Jayet and Christian Schindler and Nino K{\"u}nzli and J. P. Zellweger and Otto Braendli and Andr{\'e} Paul Perruchoud and Roland Keller and Joel Schwartz and Ursula A Ackermann-Liebrich and Philippe Leuenberger},
  journal={Respiratory Research},
  pages={131 - 131}
BACKGROUND The distribution of airway responsiveness in a general population of non-smokers without respiratory symptoms has not been established, limiting its use in clinical and epidemiological practice. We derived reference equations depending on individual characteristics (i.e., sex, age, baseline lung function) for relevant percentiles of the methacholine two-point dose-response slope. METHODS In a reference sample of 1567 adults of the SAPALDIA cross-sectional survey (1991), defined by… CONTINUE READING