Reference ranges for exhaled nitric oxide derived from a random community survey of adults.
@article{Travers2007ReferenceRF,
title={Reference ranges for exhaled nitric oxide derived from a random community survey of adults.},
author={Justin Travers and Suzanne Marsh and Sarah Aldington and Mathew V Williams and Philippa Shirtcliffe and Alison Pritchard and Mark W Weatherall and Richard Beasley},
journal={American journal of respiratory and critical care medicine},
year={2007},
volume={176 3},
pages={
238-42
}
}RATIONALE
Measurement of the fraction of nitric oxide in exhaled breath (Fe(NO)) has been proposed as a noninvasive marker of airway inflammation. Before the widespread use of this test, there is a need to develop reference ranges to allow clinicians to interpret Fe(NO) measurements.
OBJECTIVES
To derive reference ranges for Fe(NO) and to determine which factors in health and disease influence Fe(NO) levels.
METHODS
Subjects aged between 25 and 75 years were drawn from a random sample of…
Topics from this paper
216 Citations
Reference ranges for exhaled nitric oxide fraction in healthy Japanese adult population.
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It seems reasonable that the upper limit of FE(NO) for healthy adults should be set at approximately 36.0 ppb irrespective of ethnic differences, which is similar to those of Caucasians.
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Reference ranges and the diagnostic utility of FeNO levels for asthma in Korean elderly adults are presented and gender is identified as an independent determinant forFeNO levels.
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The reference values of FENO for non-smoking, non-atopic male Saudi adults fall between 7.66 and 46.6 ppb, similar to other populations, and the FENNO negatively correlates with body weight and BMI.
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The cutoff values presented may be useful for the interpretation of FE(NO) values in the clinical practice and shown to be associated with the highest combination of sensitivity and specificity.
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The reference ranges for FeNO in healthy Egyptian adults were similar to those of the Caucasian population, and values of more than 50 parts per billion in male participants and 40 ppb in female participants are considered abnormal in Egyptian populations.
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The present FeNO norms enrich the global repository of FeNOnorms that the clinician can use to choose the most appropriate norms to establish and assess their reliability.
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