Reference range concentrations of N-acetyl-S-(2-hydroxyethyl)-L -cysteine, a common metabolite of several volatile organic compounds, in the urine of adults in the United States

@article{Calafat1999ReferenceRC,
  title={Reference range concentrations of N-acetyl-S-(2-hydroxyethyl)-L -cysteine, a common metabolite of several volatile organic compounds, in the urine of adults in the United States},
  author={Antonia M. Calafat and Dana Boyd Barr and James L. Pirkle and David L. Ashley},
  journal={Journal of Exposure Analysis and Environmental Epidemiology},
  year={1999},
  volume={9},
  pages={336-342}
}
N-acetyl- S-(2-hydroxyethyl)- L-cysteine (2-hydroxyethyl mercapturic acid, HEMA) is a urinary metabolite of several hazardous chemicals, including vinyl chloride (VC), ethylene oxide (EO), and ethylene dibromide (EDB). Information about the levels of HEMA in the general population is useful for assessing human exposures to HEMA parent compounds, including VC, EO, and EDB. To establish reference range concentrations for HEMA, we analyzed urine samples from 412 adult participants in the Third… CONTINUE READING