Reference genes for reverse transcription quantitative PCR in canine brain tissue

  title={Reference genes for reverse transcription quantitative PCR in canine brain tissue},
  author={Q. E. M. Stassen and F. Riemers and H. Reijmerink and P. Leegwater and L. Penning},
  journal={BMC Research Notes},
  • Q. E. M. Stassen, F. Riemers, +2 authors L. Penning
  • Published 2015
  • Medicine, Biology
  • BMC Research Notes
  • BackgroundIn the last decade canine models have been used extensively to study genetic causes of neurological disorders such as epilepsy and Alzheimer’s disease and unravel their pathophysiological pathways. Reverse transcription quantitative polymerase chain reaction is a sensitive and inexpensive method to study expression levels of genes involved in disease processes. Accurate normalisation with stably expressed so-called reference genes is crucial for reliable expression analysis… CONTINUE READING
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