Refeeding after prolonged food restriction differentially affects hypothalamic and adipose tissue leptin gene expression.


Rat adipose tissue is the principal site of leptin synthesis, however, leptin gene expression has been demonstrated in many rat tissues. Some data indicate that leptin produced by human brain and adipose tissue could cooperate in the regulation of food intake. In this case the regulation of leptin gene expression in hypothalamus and in adipose tissue should… (More)
DOI: 10.1016/j.npep.2009.05.001


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